
Cigna Commercial Membership Clinical Guidelines
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Supplemental Information
Comprehensive Musculoskeletal Management Guidelines
- Interventional Pain Management Quick Reference Guide Guideline
- Joint Surgery Quick Reference Guide Guideline
- Preface to the Comprehensive Musculoskeletal Guidelines
- Preface to the Comprehensive Musculoskeletal Guidelines - Effective 07/01/2025
Interventional Pain and Joint Surgery
- Ablations/Denervations of Facet Joints and Peripheral Nerves (CMM-208) Guideline
- Ablations/Denervations of Facet Joints and Peripheral Nerves (CMM-208) Guideline - Effective 07/01/2025
- Epidural Adhesiolysis (CMM-207) Guideline
- Epidural Adhesiolysis (CMM-207) Guideline - Effective 07/01/2025
- Epidural Steroid Injections (CMM-200) Guideline
- Epidural Steroid Injections (CMM-200) Guideline - Effective 07/01/2025
- Facet Joint Injections/Medial Branch Blocks (CMM-201) Guideline - Effective 07/01/2025
- Facet Joint Injections/Medial Branch Blocks (CMM-201) Guideline
- Hip Replacement/Arthroplasty (CMM-313) Guideline
- Hip Replacement/Arthroplasty (CMM-313) Guideline - Effective 07/01/2025
- Hip Surgery Arthroscopic and Open Procedures (CMM-314) Guideline
- Hip Surgery Arthroscopic and Open Procedures (CMM-314) Guideline - Effective 07/01/2025
- Implantable Intrathecal Drug Delivery System (CMM-210) Guideline - Effective 07/01/2025
- Implantable Intrathecal Drug Delivery System (CMM-210) Guideline
- Knee Replacement Arthroplasty (CMM-311) Guideline
- Knee Replacement Arthroplasty (CMM-311) Guideline - Effective 07/01/2025
- Knee Surgery - Arthroscopic and Open Procedures (CMM-312) Guideline
- Knee Surgery - Arthroscopic and Open Procedures (CMM-312) Guideline - Effective 07/01/2025
- Prolotherapy (CMM-204) Guideline
- Prolotherapy (CMM-204) Guideline - Effective 07/01/2025
- Regional Sympathetic Blocks (CMM-209) Guideline - Effective 07/01/2025
- Regional Sympathetic Blocks (CMM-209) Guideline
- Sacroiliac Joint Procedures (CMM-203) Guideline
- Sacroiliac Joint Procedures (CMM-203) Guideline - Effective 07/01/2025
- Shoulder Arthroplasty/Replacement/Resurfacing/Revision/Arthrodesis (CMM-318) Guideline - Effective 07/01/2025
- Shoulder Arthroplasty/Replacement/Resurfacing/Revision/Arthrodesis (CMM-318) Guideline
- Shoulder Surgery Arthroscopic and Open Procedures (CMM-315) Guideline
- Shoulder Surgery Arthroscopic and Open Procedures (CMM-315) Guideline - Effective 07/01/2025
- Spinal Cord and Dorsal Root Ganglion Stimulation (CMM-211) Guideline
- Spinal Cord and Dorsal Root Ganglion Stimulation (CMM-211) Guideline - Effective 07/01/2025
Spine Surgery
- Ablations/Denervations of Facet Joints and Peripheral Nerves (CMM-208) Guideline
- Ablations/Denervations of Facet Joints and Peripheral Nerves (CMM-208) Guideline - Effective 07/01/2025
- Anterior Cervical Discectomy and Fusion (CMM-601) Guideline
- Anterior Cervical Discectomy and Fusion (CMM-601) Guideline - Effective 07/01/2025
- Cervical Microdiscectomy (CMM-605) Guideline
- Cervical Microdiscectomy (CMM-605) Guideline - Effective 07/01/2025
- Cervical Total Disc Arthroplasty (CMM-602) Guideline - Effective 07/01/2025
- Cervical Total Disc Arthroplasty (CMM-602) Guideline
- Discography (CMM-401)
- Discography (CMM-401) Guideline - Effective 07/01/2025
- Electrical and Low Frequency US Bone Growth Stimulation Spine (CMM-615) Guideline
- Electrical and Low Frequency US Bone Growth Stimulation Spine (CMM-615) Guideline - Effective 07/01/2025
- Grafts (CMM-612) Guideline - Effective 07/01/2025
- Grafts (CMM-612) Guideline
- Intradiscal Procedures (CMM-308) Guideline - Effective 07/01/2025
- Intradiscal Procedures Guidelines (CMM-308)
- Lumbar Decompression (CMM-608) Guideline - Effective 07/01/2025
- Lumbar Decompression (CMM-608) Guideline
- Lumbar Fusion (Arthrodesis) (CMM-609) Guideline - Effective 07/01/2025
- Lumbar Fusion (Arthrodesis) (CMM-609) Guideline
- Lumbar Microdiscectomy (Laminotomy, Laminectomy, or Hemilaminectomy) (CMM-606) Guideline - Effective 07/01/2025
- Lumbar Microdiscectomy (Laminotomy, Laminectomy, or Hemilaminectomy) (CMM-606) Guideline
- Lumbar Total Disc Arthroplasty (CMM-610) Guideline
- Lumbar Total Disc Arthroplasty (CMM-610) Guideline - Effective 07/01/2025
- Posterior Cervical Decompression (Laminectomy/ Hemilaminectomy/ Laminoplasty) (CMM-603) Guideline
- Posterior Cervical Decompression (Laminectomy/ Hemilaminectomy/ Laminoplasty)(CMM-603) Guideline - Effective 07/01/2025
- Posterior Cervical Fusion (CMM-604) Guideline
- Posterior Cervical Fusion (CMM-604) Guideline - Effective 07/01/2025
- Preface to Spine Surgery (CMM-600) Guideline - Effective 07/01/2025
- Preface to Spine Surgery (CMM-600) Guideline
- Primary Vertebral Augmentation (Percutaneous Vertebroplasty-Kyphoplasty) and Sacroplasty (CMM-607) Guideline
- Primary Vertebral Augmentation (Percutaneous Vertebroplasty-Kyphoplasty) and Sacroplasty (CMM-607) Guideline - Effective 07/01/2025
- Sacroiliac Joint Fusion or Stabilization (CMM-611) Guideline - Effective 07/01/2025
- Sacroiliac Joint Fusion or Stabilization (CMM-611) Guideline
- Thoracic and Thoracolumbar Fusion (Arthrodesis) (CMM-614) Guideline - Effective 07/01/2025
- Thoracic and Thoracolumbar Fusion (Arthrodesis) (CMM-614) Guideline
- Thoracic Decompression and Discectomy (CMM-613) Guideline
- Thoracic Decompression and Discectomy (CMM-613) Guideline - Effective 07/01/2025
- Vertebral Body Tethering for Adolescent Idiopathic Scoliosis (CMM-616) Guideline - Effective 07/01/2025
- Vertebral Body Tethering for Adolescent Idiopathic Scoliosis (CMM-616) Guideline
Gastrointestinal Endoscopic Procedure Guidelines
- Esophagogastroduodenoscopy (EGD)
- Esophagogastroduodenoscopy (EGD) Guidelines - Effective 05/01/2025
- Gastrointestinal Endoscopic Procedure: Capsule Endoscopy Guidelines
- Gastrointestinal Endoscopic Procedure: Capsule Endoscopy Guidelines - Effective 05/01/2025
- Gastrointestinal Endoscopic Procedure: Capsule Endoscopy Guidelines - Effective 07/01/2025
High-Tech Imaging and Cardiology Guidelines
- 2024 CPT 75580 Addendum to Cardiology & Radiology Imaging Guidelines
- Preface to the Imaging Guidelines - Effective 05/15/2025
- Preface to the Imaging Guidelines
- Site of Care: High-tech Radiology
General
- Abdomen Imaging Guidelines - Effective 05/15/2025
- Abdomen Imaging Guidelines
- Breast Imaging Guidelines - Effective 07/01/2025
- Breast Imaging Guidelines
- Cardiac Imaging Guidelines
- Chest Imaging Guidelines
- Head Imaging Guidelines
- Musculoskeletal Imaging Guidelines - Effective 05/15/2025
- Musculoskeletal Imaging Guidelines
- Neck Imaging Guidelines
- Oncology Imaging Guidelines - Effective 06/15/2025
- Oncology Imaging Guidelines
- Pacemaker (CID) Guidelines
- Pelvis Imaging Guidelines
- Peripheral Nerve and Neuromuscular Disorders (PNND) Imaging Guidelines
- Peripheral Vascular Disease (PVD) Imaging Guidelines
- Spine Imaging Guidelines
- Spine Imaging Guidelines - Effective 06/15/2025
Pediatric
- Pediatric Abdomen Imaging Guidelines
- Pediatric Abdomen Imaging Guidelines - Effective 05/15/2025
- Pediatric and Special Populations Oncology Imaging Guidelines - Effective 06/15/2025
- Pediatric and Special Populations Oncology Imaging Guidelines
- Pediatric and Special Populations Spine Imaging Guidelines
- Pediatric Cardiac Imaging Guidelines
- Pediatric Chest Imaging Guidelines
- Pediatric Head Imaging Guidelines
- Pediatric Musculoskeletal Imaging Guidelines - Effective 05/15/2025
- Pediatric Musculoskeletal Imaging Guidelines
- Pediatric Neck Imaging Guidelines
- Pediatric Pelvis Imaging Guidelines
- Pediatric Peripheral Nerve and Neuromuscular Disorder (PNND) Imaging Guidelines
- Pediatric Peripheral Vascular Disease (PVD) Imaging Guidelines
Peripheral Vascular Intervention
Laboratory Management - Molecular
- Cigna Lab Management Guidelines
- Cigna Lab Management Guidelines - Effective 07/01/2025
- Lab Management Prior Authorization CPT Code List - Effective 07/01/2025
- Lab Prior Authorization CPT Code List
Administrative
- MOL.AD.107.A: Unique Test Identifiers for Non-Specific Procedure Codes - Effective 07/01/2025
- MOL.AD.107.A: Unique Test Identifiers for Non-Specific Procedure Codes
- MOL.AD.304.A: Medical Necessity Review Information Requirements - Effective 07/01/2025
- MOL.AD.304.A: Medical Necessity Review Information Requirements
- MOL.AD.314.A: Date of Service and Authorization Period Effective Date - Effective 07/01/2025
- MOL.AD.314.A: Date of Service and Authorization Period Effective Date
- MOL.AD.364.A: Special Circumstances Influencing Coverage Determinations - Effective 07/01/2025
- MOL.AD.364.A: Special Circumstances Influencing Coverage Determinations
- MOL.AD.412.A: Laboratory Billing and Reimbursement - Effective 07/01/2025
- MOL.AD.412.A: Laboratory Billing and Reimbursement
Clinical Use
- MOL.CU.109.A: Genetic Testing for Cancer Susceptibility and Hereditary Cancer Syndromes
- MOL.CU.109.A: Genetic Testing for Cancer Susceptibility and Hereditary Cancer Syndromes - Effective 07/01/2025
- MOL.CU.110.A: Genetic Testing for Carrier Status
- MOL.CU.110.A: Genetic Testing for Carrier Status - Effective 07/01/2025
- MOL.CU.111.A: Genetic Testing for Non-Medical Purposes
- MOL.CU.111.A: Genetic Testing for Non-Medical Purposes - Effective 07/01/2025
- MOL.CU.112.A: Genetic Testing for Prenatal Screening and Diagnostic Testing
- MOL.CU.112.A: Genetic Testing for Prenatal Screening and Diagnostic Testing - Effective 07/01/2025
- MOL.CU.113.A: Genetic Testing for the Screening, Diagnosis, and Monitoring of Cancer
- MOL.CU.113.A: Genetic Testing for the Screening, Diagnosis, and Monitoring of Cancer - Effective 07/01/2025
- MOL.CU.114.A: Genetic Testing to Diagnose Non-Cancer Conditions
- MOL.CU.114.A: Genetic Testing to Diagnose Non-Cancer Conditions - Effective 07/01/2025
- MOL.CU.115.A: Genetic Testing to Predict Disease Risk
- MOL.CU.115.A: Genetic Testing to Predict Disease Risk - Effective 07/01/2025
- MOL.CU.116.A: Genetic Testing by Multigene Panels
- MOL.CU.116.A: Genetic Testing by Multigene Panels - Effective 07/01/2025
- MOL.CU.117.A: Experimental, Investigational, or Unproven Laboratory Testing
- MOL.CU.117.A: Experimental, Investigational, or Unproven Laboratory Testing - Effective 07/01/2025
- MOL.CU.118.A: Pharmacogenomic Testing for Drug Toxicity and Response
- MOL.CU.118.A: Pharmacogenomic Testing for Drug Toxicity and Response - Effective 07/01/2025
- MOL.CU.119.A: Preimplantation Genetic Screening and Diagnosis
- MOL.CU.119.A: Preimplantation Genetic Screening and Diagnosis - Effective 07/01/2025
- MOL.CU.246.A: Hereditary (Germline) Testing After Tumor (Somatic) Testing
- MOL.CU.246.A: Hereditary (Germline) Testing After Tumor (Somatic) Testing - Effective 07/01/2025
- MOL.CU.256.A: Confirmatory Genetic Testing
- MOL.CU.256.A: Confirmatory Genetic Testing - Effective 07/01/2025
- MOL.CU.291.A: Genetic Testing for Known Familial Mutations - Effective 07/01/2025
- MOL.CU.291.A: Genetic Testing for Known Familial Mutations
- MOL.CU.292.A: Genetic Testing for Variants of Uncertain Clinical Significance - Effective 07/01/2025
- MOL.CU.292.A: Genetic Testing for Variants of Uncertain Clinical Significance
- MOL.CU.333.B: Medically Necessary Laboratory Testing - Effective 07/01/2025
- MOL.CU.333.B: Medically Necessary Laboratory Testing
Test Specific
- MOL.TS.124.A: Alpha-1 Antitrypsin Deficiency Testing
- MOL.TS.124.A: Alpha-1 Antitrypsin Deficiency Testing - Effective 07/01/2025
- MOL.TS.125.A: Amyotrophic Lateral Sclerosis (ALS) Genetic Testing
- MOL.TS.125.A: Amyotrophic Lateral Sclerosis (ALS) Genetic Testing - Effective 07/01/2025
- MOL.TS.126.A: Angelman Syndrome Genetic Testing
- MOL.TS.126.A: Angelman Syndrome Genetic Testing - Effective 07/01/2025
- MOL.TS.129.A: Ashkenazi Jewish Carrier Screening - Effective 07/01/2025
- MOL.TS.129.A: Ashkenazi Jewish Carrier Screening
- MOL.TS.130.A: Ataxia-Telangiectasia Genetic Testing
- MOL.TS.130.A: Ataxia-Telangiectasia Genetic Testing - Effective 07/01/2025
- MOL.TS.144.A: CADASIL Genetic Testing
- MOL.TS.144.A: CADASIL Genetic Testing - Effective 07/01/2025
- MOL.TS.148.A: Charcot-Marie-Tooth Neuropathy Genetic Testing - Effective 07/01/2025
- MOL.TS.148.A: Charcot-Marie-Tooth Neuropathy Genetic Testing
- MOL.TS.150.A: Chromosomal Microarray Testing For Developmental Disorders (Prenatal and Postnatal)
- MOL.TS.150.A: Chromosomal Microarray Testing For Developmental Disorders (Prenatal and Postnatal) - Effective 07/01/2025
- MOL.TS.158.A: Cystic Fibrosis Genetic Testing
- MOL.TS.158.A: Cystic Fibrosis Genetic Testing - Effective 07/01/2025
- MOL.TS.162.A: Early Onset Familial Alzheimer Disease Genetic Testing
- MOL.TS.162.A: Early Onset Familial Alzheimer Disease Genetic Testing - Effective 07/01/2025
- MOL.TS.165.C Carrier Screening Panels, Including Targeted, Pan-Ethnic, Universal, and Expanded
- MOL.TS.165.C Carrier Screening Panels, Including Targeted, Pan-Ethnic, Universal, and Expanded - Effective 07/01/2025
- MOL.TS.168.A: Familial Adenomatous Polyposis Genetic Testing - Effective 07/01/2025
- MOL.TS.168.A: Familial Adenomatous Polyposis Genetic Testing
- MOL.TS.169.A: Familial Hypercholesterolemia Genetic Testing
- MOL.TS.169.A: Familial Hypercholesterolemia Genetic Testing - Effective 07/01/2025
- MOL.TS.170.A: Familial Malignant Melanoma Genetic Testing
- MOL.TS.170.A: Familial Malignant Melanoma Genetic Testing - Effective 07/01/2025
- MOL.TS.182.A: Hereditary Cancer Syndrome Multigene Panels
- MOL.TS.182.A: Hereditary Cancer Syndrome Multigene Panels - Effective 07/01/2025
- MOL.TS.183.A: HFE Hemochromatosis Genetic Testing
- MOL.TS.183.A: HFE Hemochromatosis Genetic Testing - Effective 07/01/2028
- MOL.TS.193.A: Li-Fraumeni Syndrome Genetic Testing
- MOL.TS.193.A: Li-Fraumeni Syndrome Genetic Testing - Effective 07/01/2025
- MOL.TS.194.A: Liquid Biopsy Testing
- MOL.TS.194.A: Liquid Biopsy Testing - Effective 07/01/2025
- MOL.TS.197.A: Lynch Syndrome Genetic Testing
- MOL.TS.197.A: Lynch Syndrome Genetic Testing - Effective 07/01/2025
- MOL.TS.202.A: Marfan Syndrome Genetic Testing
- MOL.TS.202.A: Marfan Syndrome Genetic Testing - Effective 07/01/2025
- MOL.TS.206.A: MUTYH Associated Polyposis Genetic Testing
- MOL.TS.206.A: MUTYH Associated Polyposis Genetic Testing - Effective 07/01/2025
- MOL.TS.209.A: Non-Invasive Prenatal Screening
- MOL.TS.209.A: Non-Invasive Prenatal Screening - Effective 07/01/2025
- MOL.TS.215.A: PCA3 Testing for Prostate Cancer
- MOL.TS.215.A: PCA3 Testing for Prostate Cancer - Effective 07/01/2025
- MOL.TS.217.A: Prader-Willi Syndrome Genetic Testing
- MOL.TS.217.A: Prader-Willi Syndrome Genetic Testing - Effective 07/01/2025
- MOL.TS.223.A: PTEN Hamartoma Tumor Syndromes Genetic Testing - Effective 07/01/2025
- MOL.TS.223.A: PTEN Hamartoma Tumor Syndromes Genetic Testing
- MOL.TS.225.A: Spinal Muscular Atrophy Genetic Testing - Effective 07/01/2025
- MOL.TS.225.A: Spinal Muscular Atrophy Genetic Testing
- MOL.TS.227.A: Thoracic Aortic Aneurysms and Dissections (TAAD) Panel Genetic Testing
- MOL.TS.227.A: Thoracic Aortic Aneurysms and Dissections (TAAD) Panel Genetic Testing - Effective 07/01/2025
- MOL.TS.228.A: Tissue of Origin Testing for Cancer of Unknown Primary
- MOL.TS.228.A: Tissue of Origin Testing for Cancer of Unknown Primary - Effective 07/01/2025
- MOL.TS.230.C: Somatic Mutation Testing - Effective 07/01/2025
- MOL.TS.230.C: Somatic Mutation Testing
- MOL.TS.232.A: VeriStrat Testing for NSCLC TKI Response
- MOL.TS.232.A: VeriStrat Testing for NSCLC TKI Response - Effective 07/01/2025
- MOL.TS.235.C: Exome Sequencing - Effective 07/01/2025
- MOL.TS.235.C: Exome Sequencing
- MOL.TS.238.A: BRCA Analysis - Effective 07/01/2025
- MOL.TS.238.A: BRCA Analysis
- MOL.TS.240.A: BCR-ABL Negative Myeloproliferative Neoplasm Testing
- MOL.TS.248.A: Breast Cancer Index for Breast Cancer Prognosis
- MOL.TS.248.A: Breast Cancer Index for Breast Cancer Prognosis - Effective 07/01/2025
- MOL.TS.251.A: PALB2 Genetic Testing for Breast Cancer Risk - Effective 07/01/2025
- MOL.TS.251.A: PALB2 Genetic Testing for Breast Cancer Risk
- MOL.TS.254.A: DecisionDX Uveal Melanoma
- MOL.TS.254.A: DecisionDX Uveal Melanoma - Effective 07/01/2025
- MOL.TS.257.A: Epilepsy Genetic Testing
- MOL.TS.257.A: Epilepsy Genetic Testing - Effective 07/01/2025
- MOL.TS.258.A: Maturity-Onset Diabetes of the Young (MODY) Genetic Testing
- MOL.TS.258.A: Maturity-Onset Diabetes of the Young (MODY) Genetic Testing - Effective 07/01/2025
- MOL.TS.266.A: Mitochondrial Disorders Genetic Testing
- MOL.TS.266.A: Mitochondrial Disorders Genetic Testing - Effective 07/01/2025
- MOL.TS.267.A: Ehlers-Danlos Syndrome Genetic Testing - Effective 07/01/2025
- MOL.TS.267.A: Ehlers-Danlos Syndrome Genetic Testing
- MOL.TS.268.A: Hereditary Connective Tissue Disorder Genetic Testing
- MOL.TS.268.A: Hereditary Connective Tissue Disorder Genetic Testing - Effective 07/01/2025
- MOL.TS.269.A: Autism, Intellectual Disability, and Developmental Delay Genetic Testing
- MOL.TS.269.A: Autism, Intellectual Disability, and Developmental Delay Genetic Testing - Effective 07/01/2025
- MOL.TS.271.A: PancraGEN - Effective 07/01/2025
- MOL.TS.271.A: PancraGEN
- MOL.TS.273.A: Nonsyndromic Hearing Loss and Deafness Genetic Testing
- MOL.TS.273.A: Nonsyndromic Hearing Loss and Deafness Genetic Testing - Effective 07/01/2025
- MOL.TS.276.A: Polymerase Gamma (POLG) Related Disorders Genetic Testing
- MOL.TS.276.A: Polymerase Gamma (POLG) Related Disorders Genetic Testing - Effective 07/01/2025
- MOL.TS.282.A: DermTech Pigmented Lesion Assay
- MOL.TS.282.A: DermTech Pigmented Lesion Assay - Effective 07/01/2025
- MOL.TS.287.A: Hereditary Pancreatitis Genetic Testing
- MOL.TS.287.A: Hereditary Pancreatitis Genetic Testing - Effective 07/01/2025
- MOL.TS.288.A: Limb-Girdle Muscular Dystrophy Genetic Testing - Effective 07/01/2025
- MOL.TS.288.A: Limb-Girdle Muscular Dystrophy Genetic Testing
- MOL.TS.290.A: Facioscapulohumeral Muscular Dystrophy Genetic Testing
- MOL.TS.290.A: Facioscapulohumeral Muscular Dystrophy Genetic Testing - Effective 07/01/2025
- MOL.TS.294.A: Decipher Prostate Cancer Classifier
- MOL.TS.294.A: Decipher Prostate Cancer Classifier - Effective 07/01/2025
- MOL.TS.301.A: Neurofibromatosis Type 1 Genetic Testing - Effective 07/01/2025
- MOL.TS.301.A: Neurofibromatosis Type 1 Genetic Testing
- MOL.TS.302.A: Legius Syndrome Genetic Testing
- MOL.TS.302.A: Legius Syndrome Genetic Testing - Effective 07/01/2025
- MOL.TS.306.C: Genome Sequencing
- MOL.TS.306.C: Genome Sequencing - Effective 07/01/2025
- MOL.TS.307.A: AlloSure for Kidney Transplant Rejection - Effective 07/01/2025
- MOL.TS.307.A: AlloSure for Kidney Transplant Rejection
- MOL.TS.309.A: Friedreich Ataxia Genetic Testing - Effective 07/01/2025
- MOL.TS.309.A: Friedreich Ataxia Genetic Testing
- MOL.TS.310.A: Hereditary Ataxia Multigene Panel Testing - Effective 07/01/2025
- MOL.TS.310.A: Hereditary Ataxia Multigene Panel Testing
- MOL.TS.311.A: Spinocerebellar Ataxia Genetic Testing - Effective 07/01/2025
- MOL.TS.311.A: Spinocerebellar Ataxia Genetic Testing
- MOL.TS.324.A: CHARGE Syndrome and CHD7 Disorder Genetic Testing (previously CHARGE Syndrome Genetic Testing) - Effective 07/01/2025
- MOL.TS.324.A: CHARGE Syndrome and CHD7 Disorder Genetic Testing (previously CHARGE Syndrome Genetic Testing)
- MOL.TS.344.A: Chromosomal Microarray for Solid Tumors - Effective 07/01/2025
- MOL.TS.344.A: Chromosomal Microarray for Solid Tumors
- MOL.TS.359.A: Inflammatory Bowel Disease Biomarker Testing - Effective 07/01/2025
- MOL.TS.359.A: Inflammatory Bowel Disease Biomarker Testing
- MOL.TS.360.A: Inherited Bone Marrow Failure Syndrome (IBMFS) Testing - Effective 07/01/2025
- MOL.TS.360.A: Inherited Bone Marrow Failure Syndrome (IBMFS) Testing
- MOL.TS.361.A: Human Platelet and Red Blood Cell Antigen Genotyping
- MOL.TS.361.A: Human Platelet and Red Blood Cell Antigen Genotyping - Effective 07/01/2025
- MOL.TS.371.A: Noonan Spectrum Disorder Genetic Testing
- MOL.TS.371.A: Noonan Spectrum Disorder Genetic Testing - Effective 07/01/2025
- MOL.TS.396.A: Multi-Cancer Early Detection Screening
- MOL.TS.396.A: Multi-Cancer Early Detection Screening - Effective 07/01/2025
- MOL.TS.410.A: Cardiomyopathy and Arrhythmia Genetic Testing
- MOL.TS.410.A: Cardiomyopathy and Arrhythmia Genetic Testing - Effective 07/01/2025
- MOL.TS.419.A: Primary Ciliary Dyskinesia Genetic Testing - Effective 07/01/2025
Radiation & Medical Oncology Guidelines
Medical Oncology
Radiation Oncology
Physician Worksheets
- Adrenal Cancer Physician Worksheet
- Anal Canal Cancer Worksheet
- Bile Duct Cancer Physician Worksheet
- Bladder Cancer Physician Worksheet
- Bone Metastases - Xofigo Physician worksheet
- Bone Metastases Physician Worksheet
- Brain Metastases Physician Worksheet
- Breast Cancer Physician Worksheet
- Central Nervous (CNS) Lymphoma Physician Worksheet
- Central Nervous (CNS) Neoplasm Physician Worksheet
- Cervical Cancer Physician Worksheet
- Endometrial Cancer Physician Worksheet
- Esophageal Cancer Physician Worksheet
- Extracranial Oligometastases Physician Worksheet
- Gallbladder Cancer Physician Worksheet
- Gastric (Stomach) Cancer Physician Worksheet
- Head and Neck Cancer Physician Worksheet
- Hepatobiliary Cancer Physician Worksheet
- Hodgkin's Lymphoma Physician Worksheet
- Hyperthermia Physician Worksheet
- Kidney Cancer Physician Worksheet
- Liver Cancer Physician Worksheet
- Liver Cancer, Selective Internal Radiation Therapy Physician Worksheet
- Lung Cancer, Small Cell Physician Worksheet
- Multiple Myeloma Cancer Physician Worksheet
- Non-Cancerous Diagnosis Physician Worksheet
- Non-Hodgkin's Lymphoma Physician Worksheet
- Non-Small Cell Lung Cancer Physician Worksheet
- Other Cancer Type Physician Worksheet
- Other Metastases (non-Bone/Brain) Physician Worksheet
- Pancreatic Cancer Physician Worksheet
- Prophylactic Cranial Irradiation (PCI) Radiation Therapy Physician Worksheet
- Prophylactic Cranial Irradiation (PCI) Radiation Therapy Physician Worksheet
- Prostate Cancer Physician Worksheet
- Radiopharmaceuticals Physician Worksheet
- Rectal Cancer Physician Worksheet
- Skin Cancer Physician Worksheet
- Soft Tissue Sarcoma Physician Worksheet
- Testicular Cancer Physician Worksheet
- Ureter/Urethral Cancer Physician Worksheet
- Vulva Cancer Physician Worksheet
Additional Information
Other Cigna guidelines and policies that may be relevant are available on the Cigna website.
For questions or comments regarding EviCore's Guidelines
EviCore's clinical guidelines are evidence-based and apply to the following categories of service for individuals with Cigna-administered plans:
- Computed Tomography (CT) and Computed Tomography Angiography (CTA)
- Magnetic Resonance Imaging (MRI) and Magnetic Resonance Angiography (MRA)
- Positron Emission Tomography (PET)
- Nuclear Cardiology
- Cardiac Stress Echocardiography
- Diagnostic Cardiac Catheterization
- Pain Management
- Major Joint Surgery
- Radiation Therapy (Oncology)
The terms of an individual's particular coverage plan document [Group Service Agreement (GSA), Evidence of Coverage, Certificate of Coverage, Summary Plan Description (SPD), or similar plan document] may differ significantly from the standard coverage plans upon which these guidelines are based. If these clinical guidelines are inconsistent with the terms of the individual's specific coverage plan, then the terms of the individual's coverage plan always takes precedence.
Coverage determinations in each specific instance require consideration of:
- The terms of the applicable coverage plan document in effect on the date of service
- Any applicable laws or regulations
- Any relevant collateral source materials including clinical guidelines
- The specific facts of the particular situation
EviCore's guidelines are based upon major national and international association and society guidelines and criteria, peer-reviewed literature, major treatises, and input from health plans, practicing academic and community-based physicians.
Medical technology is continuously evolving; the guidelines undergo a formal review annually, however EviCore reserves the right to change and update the guidelines without prior notice. Additional clinical guidelines may be developed as needed or may be withdrawn from use.
These guidelines are not intended to supersede or replace sound medical judgment, but instead should facilitate the identification of the most appropriate imaging procedure given the individual's clinical condition. These guidelines are written to cover medical conditions as experienced by the majority of individuals. However, these guidelines may not be applicable in certain clinical circumstances. EviCore's clinical guidelines may include information inapplicable to benefit plans administered by Cigna.
Clinical decisions, including treatment decisions, are the responsibility of the individual and his/her provider. Clinicians are expected to use independent medical judgment which takes into account the clinical circumstances to make individual management decisions.
EviCore supports the work of physicians and others who strive to reduce the overuse of diagnostic tests that are of low value, of no value, or where the risks of a given diagnostic test are greater than the benefits.
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